This Weekly Review, from October 25, 2022, draws from the Second Round of the EVD Knowledge, Attitudes, and Practices (KAP) assessment conducted in South Sudan in 2019 to highlight the implications of the recent Ebola Virus Disease events in Uganda on South Sudan. We focus attention on key risk areas, namely general awareness on infection sources, symptoms/signs, transmission modes, and how these outcomes vary by place (i.e., county) and sociodemographic factors (i.e., education, gender, age, and religion).

Understanding people’s knowledge on the above and its relation to one’s residence and sociodemographic factors can help better inform the Ministry of Health’s preparedness and readiness to respond to a potential EVD outbreak. Key lessons learned include that community engagement is key to successfully controlling outbreaks.