The stigmatization of Senegalese return migrants as COVID-19 vectors by fellow Senegalese during the early days of the COVID-19 pandemic troubles the self/other distinction that underpins the scholarly focus on epidemics and xenophobia and encourages the broader task of exploring epidemics and phobia. The casting of return migrants as COVID-19 vectors was influenced by longstanding ambivalence toward these migrants that had encouraged some Senegalese to seek to “confine” them to Europe long before the pandemic. Old preoccupations help us understand how Senegalese interpreted and deployed COVID-19 control and prevention measures like “confinement,” lockdowns, and border closures.